JCT - Faculty Research Profile - 2017-2021

121 Mrs. Yaacov-Vardi Oriya Cell phone: 0527203328 Email: oriyavardi@gmail.com My main interest is in genomics. Specifically, I study the relationships between replication timing and mutation rate in cancer. Peer-Reviewed Papers in Refereed Journals 1. Adar Yaacov*, Oriya Vardi*, Britny Blumenfeld, Avraham Greenberg, Dashiell J Massey, Amnon Koren, Sheera Adar, Itamar Simon, Shai Rosenberg. Cancer mutational processes vary in their association with replication timing and chromatin accessibility. (2021) Cancer Res. (IF: 11.1, Q1) *Equal contribution 2. Britny Blumenfeld, Hagit Masika, Marganit Farago, Yishai Yehuda, Lamia Halaseh, Oriya Vardi, Rachel Rapoport, Rena Levin-Klein, Howard Cedar, Yehudit Bergman, Itamar Simon. (2021) Chromosomal coordination and differential structure of asynchronous replicating regions. Nat Commun (IF:13.6, Q1) 3. Yishai Yehuda, Britny Blumenfeld, Nina Mayorek, Kirill Makedonski, Oriya Vardi, Leonor Cohen-Daniel, Yousef Mansour, Shulamit Baror-Sebban, Hagit Masika, Marganit Farago, Michael Berger, Shai Carmi, Yosef Buganim, Amnon Koren, Itamar Simon. (2018). Germline DNA replication timing shapes mammalian genome composition. Nucleic Acids Res. (IF:11.5, Q1) 4. Oriya Vardi, Inbal Shamir, Elisheva Javasky, Alon Goren, Itamar Simon. (2017) Biases in the SMART-DNA library preparation method associated with genomic poly dA/dT sequences. PLoS One. (IF: 3.2, Q1)

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