פרידמן

לפרטים על תואר ראשון ושני

למידע נוסף על לימודים אקדמיים בלבד השאירו פרטיכם ונחזור בהקדם

ראשי » פרידמן
ד"ר פרידמן זאב יהודה ,
מרצה
  • בתיאום מראש

Curriculum Vitae
קורות חיים

Education

השכלה

 

 

 

B.Sc. in Chemistry, Tel-Aviv University, Israel 1973

Ph.D. in Biochemistry, Hebrew University of Jerusalem, Israel, 1983

 

Work Experience

ניסיון עבודה

1984-1986  Post-doctoral fellowship in Hebrew University Life Sciences Institute on ras oncogenic transformations.

1987 – 1994 Research in Hebrew University Biochemistry Department on phosphoinositides metabolism 

1995 – 2002 Research in Hebrew University Biochemistry Department on mechanism of secretion from rat parotid gland

2003 – Lecturer Bioinformatics Department, Jerusalem College of Technology, Israel

 

Publication

פרסומים

1.       Friedman ZY and Selinger Z (1978) A transient release of potassium mediated by the action of substance P on rat parotid slices.

          J.Physiol.278:461-469                                              

2.       Laufer R,Chorev M,Gilon C,Friedman ZY,Wormser U and Selinger Z (1981) Persistent action of N-methylated analogs of substance P on rat parotid slices.

          FEBS Lett.123:291-294                                               

3.       Friedman ZY,Lowe M and Selinger Z (1981) Beta-adrenergic receptor stimulated peroxidase secretion from rat lacrimal gland.

          Biochim.Biophys.Acta 675:40-45                                     

4.       Chorev M,Gilon C,Wormser U,Friedman ZY and Selinger Z.(1981)

          Structural requirement of the N-acylating residue to substance P partial sequence .

          Proceedings of the 16th EPS (K.Branfeld ed.) Scriptor,Copenhagen pp.451- 456                                                          

5.       Rubini E,Chorev M,Gilon C,Friedman ZY,Wormser U and Selinger Z (1981) Enzymatically stable,partially modified retro-inverso analogs of substance P synthesis and biological activity.

          In:Peptides-Synthesis-Structure-Function,Proceedings of the 7th American Peptide Symposium(D.H.Rich and E.Gross,eds.) Pierce Chmical Co.,Rockford,Il.pp.593-597                                         

6.       Atlas D,Friedman ZY,Litvin Y and Steer MZ(1982) Synthesis of new haloperidol analogs and characterization of their interactions with the alpha-adrenoceptors in rat parotid slices and human platelet membranes.

          Br.J.Pharmacol.75:213-217                                          

7.       Wormser U,Chorev M,Gilon C,Laufer R,Friedman ZY and Selinger Z(1984) Substance P degrading systems of rat parotid and hypothalamus.

          Biochim.Biophys.Acta 798:28-36

8.       Friedman ZY Wormser U Rubini E,Chorev M,Gilon C and Selinger Z (1985) Desensitization of substance P induced K+ release in rat parotid.

          Eur.J.Pharmacol.117:323-328

9.       Laufer R,Wormser U, Friedman ZY,Gilon C,Chorev M and Selinger Z (1985) Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin.

          Proc.Natl.Acad.Sci.U.S.A.82:7444-7447  

10.     Friedman ZY, Selinger Z, Karmeli F, Eliakim R, and Rachmilewits, D. (1992) Enhanced colonic inositol phosphate generation in Crohn's disease and inhibition of its formation by ketotifen.

          Gastroenterology, 102, A-623

11.     Friedman ZY (1993) Tamoxifen and vanadate synergize in causing accumulation of polyphosphoinositides in membranes of GH4C1 cells.

          J. Pharmacol. Exp. Ther., 267:617-623

12.     Friedman ZY (1994) The antitumor agent tamoxifen inhibits breakdown of polyphosphoinositides in GH4C1 cells.

          J. Pharmacol. Exp. Ther. 271:238-245

13. Friedman ZY (1998) Recent advances in understanding the molecular mechanisms of tamoxifen action.

          Cancer Investigations. 16:391-396

14. Friedman ZY, Devary Y. (2005) Dissection of the GTPase mechanism of Ras protein by MD analysis of Ras mutants.

          PROTEINS: Structure, Function and Bioinformatics. 59:528-533